Mammalian and human FXI-T1

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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536 231, C12Q 168, C07H 2102

Patent

active

060134410

ABSTRACT:
The present invention concerns the field of molecular genetics and medicine. Particularly, it concerns a gene, FXI-T1, whose mRNA levels are increased in fractionated X-irradiation induced leukemias and methods of using FXI-T1 to classify tissue samples for medical purposes. Specifically, the invention concerns the murine and human homologs of FXI-T1.

REFERENCES:
Amari, N.M.B., et al., Murine Thymomas Induced by Fractionated-X-Irradiation Have Specific T-Cell Receptor Rearrangements and Characteristics Associated with Day-15 to-16 Fetal Thymocytes. Dec. 1987, vol. 7, No. 12, pp. 4159-4168 Mol. Cell. Biol.
Pampeno, C.L., et al. A Novel cDNA Transcript Expressed in Fractionated X-Irradiation-induced Murine Thymomas. Aug. 1996, vol. 7, pp. 1113-1123. Cell Growth & Differ.
Amari, N.M.B., et al., Effects of fractionized x-irradiation on the Ly-6-Ril-1--Pol-5 region. 1990, vol. 32, pp. 252-262. Immunogenetics.

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