Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1983-10-14
1993-01-12
Doll, John
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
4351722, 4352402, 43524027, 5303884, 530865, C12N 522, C12N 1502, C07K 1528
Patent
active
051790181
ABSTRACT:
Mammalian monoclonal anti-lipopolysaccharide (LPS) antibodies which react with gram-negative bacteria across different genera are disclosed. The anti-LPS antibodies are useful for the treatment or prevention of gram-negative bacteremia and for the detection of gram-negative microorganisms.
REFERENCES:
patent: 4443549 (1984-04-01), Sadowski
patent: 4451570 (1984-05-01), Royston
patent: 4455296 (1984-06-01), Hansen
patent: 4464465 (1984-08-01), Lostrum
Kaplan, H. S. et al. Monoclonal Antibodies in Clinical Medicine, McMichael, A. J. et al., eds., Academic Press (1982) N.Y.; pp. 17-35.
Nowinski, R. C. et al., Science, 219:637-644 (Feb. 1983).
Wolf, G. L. et al., Magnetic Resonance Annual (1985), Kressel, H. Y. ed., Raven Press, N.Y. pp. 231-266.
Abrams, P. G. et al. J. of Immunol., vol. 131(3), pp. 1201-1204 (Sep. 1983).
Marks, M. I. et al., J. Clin. Invest., vol. 69(4), pp. 742-749 (Apr. 1982).
Howard, J. C. et al., Immunol. Rev., vol. 47, pp. 160-174 (1979).
Hughes-Jones, N. C. et al., Eur. J. Immunol., vol. 13, pp. 635-641 (1983).
Pollack, M. et al., Abstracts 1983 Interscience Conf. Antimicrob. Agents Chemother., Abs. 614, p. 195 (Aug. 1983).
Hiernaux, J. et al., Proc. Natl. Acad. Sci., U.S.A., vol. 79, pp. 1616-1620 (Mar. 1982).
Hiernaux, J. R. et al., Eur. J. Immunol., vol. 12(10), pp. 797-803 (1982).
Morse, S. A. et al., J. Infect. Diseases, vol. 145(2) pp. 206-216 (Feb. 1982).
Young, L. S. et al., Clinical Research, p. 522A, vol. 30 (2), (1982).
Braude, A. I. et al., J. Infect. Diseases, vol. 136, pp. S167-S173 (1977).
McCabe, W. R. et al., J. Infect. Diseases, vol. 136, pp. S164-S166 (1977).
Ziegler, E. J. et al., New England J. Medicine, vol. 307, (20), pp. 1225-1230 (Nov. 1982).
Kozbor, D. et al., Immunology Today, vol. 4(3), pp. 72-79 (1983), Applicants' Attachment A.
Levy, R. et al., Ann. Rev. Med., vol. 34, pp. 107-116 (1983), Applicants' Attachment E.
Miller, R. A. et al., The Lancet, Aug. 1, 1981, pp. 226-230, Applicants' Attachment F.
Sears, H. F. et al., The Lancet, Apr. 3, 1982, pp. 762-765, Applicants' Attachment G.
Dillman, R. O. et al., Blood, vol. 59(5), pp. 1036-1045 (1982), Applicants' Attachment H.
Hiernaux, J. et al., Proc. Natl. Acad. Sci., U.S.A., vol. 79, pp. 1616-1620 Mar. 1982.
Darveau, R. P. et al., J. Bacteriology, vol. 155(2), pp. 831-838 (1983).
Sugaswara, R. J. et al., Infec. Immun., vol. 42(3), pp. 863-868 (1983), Biosis Abstract 77059416.
Hancock, R. E. W. et al., Infec. Immun., vol. 37(1), pp. 166-171 (1982).
Hiernaux, J. R. et al., Eur. J. Immunol., vol. 12(10), pp. 797-803 (1982).
Abe et al., Jpn. J. Exp. Med. (1975) 45:355-359.
Feingold et al., Arch. Int. Med. (1965) 116:326-328.
Hancock et al., Infect. Immun. (1982) 37:166-171.
Hiernaux et al., Eur. J. Immunology (1982) 12:797-803.
Kohler et al., Nature (1975) 256:495-497.
Mackie et al., J. Immunol. (1982) 129:829-832.
Young, L. S., Principles and Practice of Infectious Disease, (1985) John Wiley and Sons, N.Y., 452-475.
Young et al., Clinical Research (1982) 30:522A.
Zeigler et al., N. Eng. J. Med. (1982) 307:1225-1230.
Olsson et al., Proc. Natl. Acad. Sci. (1980) 77:5429-5431.
Bogard, Jr. Warren C.
Kung Patrick C.
Centocor, Inc.
Doll John
Kushan Jeff
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