Maltogenic alpha-amylase variants

Details Maltogenic alpha-amylase variants Maltogenic alpha-amylase variants

1999-08-31

2000-12-19

Achutamurthy, Ponnathapu

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

C12N 928

Patent

active

061626287

ABSTRACT:
The inventors have modified the amino acid sequence of a maltogenic alpha-amylase to obtain variants with improved properties, based on the three-dimensional structure of the maltogenic alpha-amylase Novamyl. The variants have altered physicochemical properties, e.g. an altered pH optimum, improved thermostability, increased specific activity, an altered cleavage pattern or an increased ability to reduce retrogradation of starch or staling of bread.

REFERENCES:
Kim et al., Biochemistry and Molecular Biology International, vol. 41, No. 2, pp. 227-234 (1997).
Sin et al., Journal of Biotechnology, vol. 32, pp. 283-288 (1994).
Penninga et al., Biochemistry, vol. 34, pp. 3368-3376 (1995).
Biochemical Journal, vol. 316, pp. 695-696 (1996).
Christophersen et al., Starch/Starke, vol. 50, No. 1, pp. 39-45 (1998).
Bernard Henrissat, Biochem. J., vol. 280, pp. 309-316 (1991).
Tachibana et al., Journal of Fermentation and Bioengineering, vol. 83, No. 6, pp. 540-548 (1997).
Norman et al., Denpun Kagaku, vol. 39, No. 2., pp. 101-108 (1992).
Hofmann et al., J. Mol. Biol., vol. 209, pp. 793-800 (1989).
Lawson et al., J. Mol. Biol., vol. 236, pp. 590-600 (1994).
Strokopytov et al., Biochemistry, vol. 34, pp. 2234-2240 (1995).
Knegtel et al., J. Mol. Biol., vol. 256, pp. 611-622 (1996).
Boel et al., Biochemistry, vol. 29, pp. 6244-6249 (1990).
Machius et al., J. Mol. Biol., vol. 246, pp. 545-559 (1995).
Chang et al., J. Mol. Biol., vol. 229, pp. 235-238 (1993).
Kubota et al., J. Mol. Biol., vol. 38, No. 2, pp. 141-146 (1991).
Birte Svensson, Plant Molecular Biology, vol. 25, pp. 141-157 (1994).
Abstract (sequence listing) of Swiss application No. P19531.
Klein et al., J. Mol. Biol., vol. 217, pp. 737-750 (1991).
Diderichsen et al., FEMS Microbiology Letters, vol. 56, pp. 53-60 (1988).
Wind et al., Eur. J. Biochem., vol. 253, pp. 598-605 (1998).
Dalmia et al., Biotechnology and Bioengineering, vol. 47, pp. 575-584 (1995).
Jespersen et al., Biochem. J., vol. 280, pp. 51-55 (1991).
del-Rio et al., Febs Letters, vol. 416, pp. 221-224 (1997).
Holm et al., Protein Engineering, vol. 3, pp. 181-191 (1990).
Janecek et al., Febs 11085, vol. 304, pp. 1-3 (1992).

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