Malto-oligosaccharide derivatives and use thereof

Details Malto-oligosaccharide derivatives and use thereof Malto-oligosaccharide derivatives and use thereof

2005-09-06

2005-09-06

Peselev, Elli (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C514S053000, C514S054000, C536S017300, C536S017400, C536S123100

Reexamination Certificate

active

06939858

ABSTRACT:
The present invention provides a substance which strongly inhibits human α-amylase and is effective for the prevention and treatment of hyperglycemia, for example, diabetes and the diseases caused thereby, and an α-amylase inhibitor and a prophylactic or therapeutic agent for hyperglycemia containing the said substance as active principle.Maltoligosaccharide derivatives represented by the following formula:(wherein n is an integer of 0 to 2; m is an integer of 0 to 2; and X represents a hydrogen atom or a hydrophobic group) or their hydrates or physiologically acceptable salts are provided, and they are contained as active principle to prepare an α-amylase inhibitor and a prophylactic or therapeutic agent for hyperglycemia such as diabetes.

REFERENCES:
patent: 2 064 527 (1981-06-01), None
patent: WO 00/50434 (2000-08-01), None
Agricultural and Biological Chemistry, vol. 50, 639-644, 1986, Motoo Arai et al,.

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