Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-01-09
2007-01-09
Kifle, Bruce (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S212070, C514S221000, C514S450000, C540S517000, C540S522000, C540S523000, C549S354000
Reexamination Certificate
active
10933177
ABSTRACT:
The invention relates to malonamide derivatives of formulawherein each of the variables are as defined herein and to pharmaceutically acceptable acid addition salts, optically pure enantiomers, racemates and diastereomeric mixtures thereof. These compounds are γ-secretase inhibitors and may be used for the treatment of Alzheimer's disease.
REFERENCES:
patent: WO 01/77086 (2001-10-01), None
patent: WO 01/90084 (2001-11-01), None
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Flohr Alexander
Galley Guido
Jakob-Roetne Roland
Kitas Eric Argirios
Peters Jens-Uwe
Hoffmann-La Rache Inc.
Johnston George W.
Kifle Bruce
Prior Kimberly J.
Rocha-Tramaloni Patricia S.
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