Malignant endothelial cell line and uses thereof in models...

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Canine cell – per se

Reexamination Certificate

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C435S325000, C424S093700, C424S093100

Reexamination Certificate

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10655727

ABSTRACT:
An immortalized hemangiosarcoma cell line of malignant canine endothelial cells which possesses surface expression characteristics and growth factor and cytokine expression profiles typical of nonmalignant activated endothelial cells is provided. In vitro and in vivo models for angiogenesis produced from this cell line as well as methods for identifying antiangiogenic agents using these models are also provided.

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