Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Patent
1993-02-11
1994-10-25
Shippen, Michael L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
5483147, 548496, 548532, 5483391, 560 40, 560147, 560153, 560168, 560170, 560180, 560250, 560251, 560266, 562445, 562557, 562560, 562564, 562567, 562568, 562582, 562583, C07C22900
Patent
active
053591283
ABSTRACT:
The invention comprises compositions and methods for the treatment of psoriasis. The compositions comprise compounds of the formula: ##STR1##
REFERENCES:
patent: 2661374 (1953-12-01), Schechter
patent: 2977309 (1961-03-01), Godfrey
patent: 3212970 (1965-10-01), Glasser
patent: 3778502 (1973-12-01), Aubin
patent: 3983100 (1976-09-01), Balme
patent: 4131534 (1978-12-01), Just
patent: 4481353 (1984-11-01), Nyilas et al.
W. Raab, H&G Nr. 10 (1984).
A. Lahti et al., Contact Dermatitis 12, 139-140 (1985).
Schafer G., Fumarsauretherapie der Psoriasis, Arztliche Praxis 30, 61, 1757-58 (1978).
Selecta 15, 1260-61 (1984).
Thaler et al., J. Invest. Dermatol. 75, 156-158 (1980).
Steinert et al., Biochemistry of Normal and Abnormal Differentiation, eds. I. A. Bereinstein and M. Seigji, Tokyo University Press, pp. 391-406 (1980).
J. March, Advanced Organic Chemistry, 3d ed., p. 339, J. Wiley and Sons, New York (1985).
Lochmueller, C. H. et al., Direct gas chromatographic resoltuion of enantiomers on optically active mesophases. IV. Effect of structure on selectivity and liquid crystalline behavior, J. Chromat. 178, 411-417 (1979).
Meek, J. L., Derivatizing reagents for high-performance liquid chromatography detection of peptides at the picomile level, J. Chromat. 266, 401-408 (1983).
Augustine, M., N-Maleyl amino acids and peptides, Z. Chem. 25, 18-19 (1985).
Portoghese, P. S. et al., Synthesis and opioid antagonist potencies of Naltrexamine Bivalent Ligands with Conformationally Restricted Spacers, J. Med. Chem. 29, 1650-1653 (1986).
Schellenberger, V. et al., A spectrophotometric assay for the characterization of the S' subsite specificity of .alpha.-chymotrypsin, Bioch. et Bioph. Acta 869, 54-60 (1986).
Nieboer, C. et al., Systemic therapy with fumaric acid derivatives: New possibilities in the treatment of psoriasis, J. Am. Acad. Derm. 20, 601-607 (1989).
Chemical Abstract No. 83-114855b (1975).
W. M. Nygteren-Hyying et al., Fourth International Symposium on The Treatment of Psoriasis and Psoriasis-Arthritis, Jerusalem, Israel, p. 60 (Mar. 1989).
G. Zubay, Biochemistry, 2nd Edtion, p. 334, Addison-Wesley Publishing Co. (Reading, Mass.) (1984).
C. Sreeramula Chetty et al., Arch. Int. Physiol. Biochem. 90(4), 293-6 (1982).
Gouesnard, Bull. Soc. Chim. Fr., 1, 88-94 (1989).
"Hackh's Chemical Dictionary" 4th Ed., p. 609 (1969).
S. E. Poet, Aust. J. Chem., 35, 77-83 (1982).
E. Wenkert, J. Org. Chem. 50, 4681-4685 (1985).
Chemical Abstract, vol. 100: No. 23, 191667p (1984).
Chemical Abstract, vol. 54: No. 7, 6698h-6699g (1960).
A. Lahti et al., Pharmaceutical Studies on Nonimmunologic Contact Urticaria in Guinea Pigs, Arch. Dermatol. Res., 299, 44-49 (1986).
Gouesnard, Bull. Soc. Chim. Fr, (1), pp. 88-94 (1989).
"Hackh's Chemical Dictionary," 4th Ed, p. 609 (1969).
Poet, Aust. J. Chem., 35, pp. 77-83 (1982).
Wenkert, J. Org. Chem., 50, pp. 4681-4685 (1985).
Bonadies, Chem. Abst., 100: 191667p (1984).
Muller, Chem. Abst. 54:6698h-6699g (1960).
LandOfFree
Malic acid derivatives and compositions for the treatment of pso does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Malic acid derivatives and compositions for the treatment of pso, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Malic acid derivatives and compositions for the treatment of pso will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-136980