Organic compounds -- part of the class 532-570 series – Organic compounds – Chalcogen in the nitrogen containing substituent
Patent
1986-11-21
1988-10-25
Raymond, Richard L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Chalcogen in the nitrogen containing substituent
544103, 549225, 562442, 562450, 564153, 564156, 564160, C07D26528, C07D23732
Patent
active
047805358
ABSTRACT:
Conjugates of isomaleimides and isophthalimides and organic chromophoric compounds exhibiting fluorescence, luminescence, chemiluminescence or absorption of analytical value having the structural formula I and II ##STR1## wherein R is an organic aromatic molecule which may be substituted, heteroaromatic which may be substituted, aliphatic having 1 to 50 carbon atoms and which may be substituted or an organic chromophoric molecule exhibiting fluorescence, luminescence, chemiluminiescence or absorption of analytical value. R' is an organic chromophoric molecule exhibiting fluorescence, luminescence, chemiluminescence, or absorption of analytical value; R.sub.1 is hydrogen, halogen, carboxylic, alkyl, aryl, hydroxyl, amino group which may be substituted, nitro or sulfonic group. R.sub.2, R.sub.3 and R.sub.4 have the same meaning as R.sub.1 ; X is hydrogen, alkyl, aryl, halogen, carboxylic, alkoxy, aryloxy, hydroxyl, amino group which may be substituted or alkyl group forming a five or six member ring with the adjacent olefinic carbon atom; Y has the same meaning as X; Z is hydrogen, alkyl having 1 to 18 carbon atoms or aryl. The maleic diamides and the phthalic diamides of the invention may be used for the labeling of organic substrates as staining materials and as indicators.
REFERENCES:
patent: 2998425 (1961-08-01), Sauers et al.
patent: 4179466 (1979-12-01), Bollinger et al.
patent: 4433154 (1984-02-01), Hirai
patent: 4600775 (1986-07-01), Theodoropulos
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