Maleamic acid polymer derivatives and their bioconjugates

Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – From carboxylic acid or derivative thereof

Reexamination Certificate

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C528S322000, C528S363000, C525S205000, C525S540000

Reexamination Certificate

active

07994272

ABSTRACT:
The present invention is directed to maleamic acid derivatives of water soluble polymers, to chemically stable water-soluble polymer succinamic acid-active agent conjugates, and to methods for reproducibly preparing, characterizing and using such polymer reagents and their conjugates.

REFERENCES:
patent: 5585484 (1996-12-01), Acharya et al.
patent: 5766897 (1998-06-01), Braxton
patent: 5932462 (1999-08-01), Harris et al.
patent: 6017943 (2000-01-01), Acharya et al.
patent: 6180134 (2001-01-01), Zalipsky et al.
patent: 6180598 (2001-01-01), Nelson
patent: 6183738 (2001-02-01), Clark
patent: 6340742 (2002-01-01), Burg et al.
patent: 6602498 (2003-08-01), Shen
patent: 6875841 (2005-04-01), Sakanoue et al.
patent: 7329721 (2008-02-01), Kozlowski et al.
patent: 7659361 (2010-02-01), Kozlowski et al.
patent: 2001/0044526 (2001-11-01), Shen
patent: 2003/0065134 (2003-04-01), Sakanoue et al.
patent: 2004/0167287 (2004-08-01), Kozlowski et al.
patent: 2008/0146771 (2008-06-01), Kozlowski et al.
patent: 0273545 (1988-07-01), None
patent: 0318162 (1989-05-01), None
patent: 0839849 (1998-05-01), None
patent: 1172372 (2002-01-01), None
patent: 1267170 (2002-12-01), None
patent: 1283233 (2003-02-01), None
patent: 2000-191700 (2000-07-01), None
patent: 92/16221 (1992-10-01), None
patent: 93/09143 (1993-05-01), None
patent: 99/03887 (1999-01-01), None
patent: 99/64460 (1999-12-01), None
patent: 00/21594 (2000-04-01), None
patent: 01/62827 (2001-08-01), None
patent: 01/87925 (2001-11-01), None
Cantin, et al., “Polyethylene Glycol Conjugation at Cys232 Prolongs the Half-Life of alpha1 Proteinase Inhibitor”, Amer. J. of Resp. Cell & Mole. Bio., vol. 27, pp. 659-665, (2002).
Han, et al., “Sugar Transport by the Bacterial Phosphotransferase System”, The J. of Bio. Chem., vol. 265, No. 4, pp. 1996-2003, (1990).
Ishii, et al., “Effects of the State of the Succinimido-Ring on the Fluorescene and Structural Properties of Pyrene Maleimide-Labeled alpha alpha-Tropomyosin”, Biophys. J., vol. 50, pp. 75-80, (1986).
Kogan, “The Synthesis of Substituted Methoxy-Poly(Ethyleneglycol) Derivatives Suitable for Selective Protein Modification”, Synthetic Comm., vol. 22, No. 16, pp. 2417-2424, (1992).
Manjula, et al., “Cys-93-beta beta-Succinimidophenyl Polyethylene Glycol 2000 Hemoglobin A”, The J. of Bio. Chem., vol. 275, No. 8, pp. 5527-5534, (2000).
Roberts, et al., “Chemistry for peptide and protein PEGylation”, Adv. Drug Del. Rev., vol. 54, pp. 459-476, (2002).
Tsutsumi, et al., “Site-specific chemical modification with polyethylene glycol of recombinant immunotoxin anti-Tac (Fv)-PE38(LMB-2) improves Antitumor activity and reduces animal toxicity and immunogenicity”, PNAS, vol. 97, No. 15, pp. 8548-8553, (Jul. 18, 2000).
Veronese, “Peptide and protein PEGylation: a review of problem and solutions”, Biomaterials, vol. 22, pp. 405-417, (2001).
Wu, et al., “p53 protein oxidation in cultured cells in response to pyrrolidine dithiocarbamate: a novel method for relating the amount of p53 oxidation in vivo to the regulation of p53-responsive genes”, Biochem. J., vol. 351, pp. 87-93, (2000).
Nektar Transforming Therapeutics, Nektar Molecule Engineering Polyethylene Glycol and Derivatives for Advanced PEGylation, pp. 1-20, Catalog-2003, (Jul. 2003).
NOF Corporation, “PEG Derivatives, Phospholipid and Drug Delivery Materials for Pharmaceuticals”, pp. 1-46, Catalogue 2003-1st, (Jan. 2003).
NOF Corporation, “PEG Derivatives, Phospholipid and Drug Delivery Materials for Pharmaceuticals”, pp. 1-50, Catalogue 2003-2nd, (Mar. 2004).
Shearwater Polymers, Inc., pp. 2-49, (Catalog-Mar. 1995).
Shearwater Polymers, Inc., Polyethylene Glycol and Derivatives, pp. 1-53, (Catalog-Jul. 1997).
Shearwater Polymers, Inc., Polyethylene Glycol and Derivatives: Functionalized Biocompatible Polymers for Research and Pharmaaceuticals, pp. 1-50, (Catalog-2000).
Shearwater Corporation, Polyethylene Glycol and Derivatives for Biomedical Applications, pp. 1-17, (Catalog-2001).
Translations of Notice of Opposition from KNH Patentanwalte to the EPO dated Mar. 25, 2009 against European Patent EP 1 587 841.
Australian Examiner's First Report corresponding to Australian Patent Application No. 2003300139 dated Sep. 19, 2007.
Chinese First Office Action corresponding to Chinese Patent Application No. 200380108082.1 date of notification Jan. 12, 2007.
European Communication corresponding to European Patent Application No. 03 800 397.6 dated Oct. 18, 2005.
European Communication corresponding to European Patent Application No. 03 800 397.6 dated Feb. 20, 2006.
Indian First Examination Report corresponding to Indian Patent Application No. 2712/DELNP/2005 dated Nov. 13, 2007.
Japanese Notice of Reasons for Rejection corresponding to Japanese Patent Application No. 2005-508648 mailing date Jul. 21, 2009.
Mexican First Office Action corresponding to Mexican Patent Application No. 2005/007163 dated Jul. 11, 2008.
PCT International Search Report corresponding to PCT/US2003/041705 date of mailing Jul. 14, 2004.
PCT International Preliminary Examination Report corresponding to PCT/US2003/041705 date of mailing Mar. 21, 2005.

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