Male fertility-inhibiting compositions of 6-chlorodeoxy-sacchari

Details Male fertility-inhibiting compositions of 6-chlorodeoxy-sacchari Male fertility-inhibiting compositions of 6-chlorodeoxy-sacchari

1978-03-14

1980-09-30

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugated via claimed linking group, bond, chelating agent,...

536 1, 536122, A61K 3170, C07H 502

Patent

active

042255902

ABSTRACT:
A male fertility-inhibiting composition in unit dosage form, contains as an active ingredient a 6-chlorodeoxy-saccharide containing a pyranose or furanose ring of the formula ##STR1## where A represents the remainder of the pyranose or furanose ring, and has the formula C.sub.4 H.sub.7 O.sub.4 X (where X represents a hydrogen atom or another pyranose or furanose ring) in association with a physiologically acceptable carrier or excipient. The saccharide preferably contains a pyranose ring or furanose ring of the formula ##STR2## Also a method of controlling fertility in men or male animals comprises administering thereto a 6-chlorodeoxy-saccharide as defined above.

REFERENCES:
patent: 2684961 (1954-08-01), Barham
Khan et al., Carbohydrate Research 39 (1975), 253-262.
Evan and Parrish, Methods in Carbohydrate Chemistry, vol. VI (1972), p. 193.
Brauns, J. Amer. Chem. Soc. 42, (1920), 1850.
Wood et al., J. Chem. Soc.(c), 1966, pp. 1994-1997.
Ford, W., and Waites, G., J. Reprod. Fert. (1978), 52, 153-157.
Ford, W., et al., J. Reprod. Fert. (1977) 51, 105-109.
Chem. Abstract Citation, vol. 83 (59219v) 1975.

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