Male contraceptive implant

Details Male contraceptive implant Male contraceptive implant

1996-02-23

1998-03-31

Azpuru, Carlos

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

5147723, A61F 202, A61K 4732

Patent

active

057335656

ABSTRACT:
The present invention relates to implantable male contraceptive devices. An ethylene vinyl acetate copolymer based implant is described for delivery of an androgen and a system including an ethylene vinyl acetate copolymer based implant as well as a second implant are described for the administration of both androgen and a sterilitant. These implants may be used to provide contraception for men, as well as, for hormone therapy, treatment of enlarged prostate and other aliments.

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patent: 5035891 (1991-07-01), Runkel et al.
patent: 5266325 (1993-11-01), Kuzma et al.
patent: 5292515 (1994-03-01), Moro et al.
"Chemical Abstracts Search," Aug. 24, 1995, 65 pages.
"Contraception With Long-Acting Subdermal Implants," The International Committee For Contraception Research Of The Population Council, Mar. 20, 1985, 351-359.
"Clinical Trial With 3-Keto-Desogestrel Subdermal Implants," Center For Biomedical Research, The Population Council, Oct. 1991, vol. 44, No. 4, 393-408.
"Contraception With Subdermal Implants Releasing The Progestin ST-1435: A Dose-Finding Study," Jan. 1992, vol. 45, No. 1, 49-55.
"7.alpha.-Methyl-Nortestosterone (MENT): The Optimal Androgen For Male Contraception," Sundaran et al., Recent Advances in Female Reproductive Health Care, 199-205.
"Long-Term Contraception With A Single Implant Of The Progestin ST-1435," Coutinho et al., Fertility& Sterility. vol. 36, No. 6, Dec. 1981, 737-740.
"ST-1435: Development of An Implant," Odlind et al., 441-449.
Contraception, Mar. 1982, vol. 25, No. 3, 300-306.
"A Contraceptive Subdermal Implant Releasing Progestin ST-1435: Ovarian Function, Bleeding Patterns and Side Effects," Laurikka-Routti et al., Fertility & Sterility, vol. 58, No. 6, Dec. 1992, 1142-1147.
"Endometrial Effects Of Transdermal Estradiol & Progestin ST-1435 In Post Menopausal Women," Suhonen et al., Fertility &Sterility, vol. 57, No. 6, Jun. 1992, 1211-1215.

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