Malate salt of...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C544S364000, C544S405000, C546S296000

Reexamination Certificate

active

08030316

ABSTRACT:
The present invention relates to a process for the preparation of compounds which are therapeutically active in the central nervous system.In one aspect, the invention relates to a process for the preparation of compounds of the general formula (I):wherein HA is a pharmaceutically acceptable acid and R1-R4are each independently selected from the group consisting of hydrogen, halogen, C1-C6-alkyl, C1-C6-alkoxy, and di-C1-C6-alkylamino-C2-C6-alkoxy.The invention also relates to the use of said compound to manufacture a medicament for the treatment of a serotonin-related disorder.

REFERENCES:
patent: WO 00/76984 (2000-12-01), None
patent: WO 00/76984 (2000-12-01), None
Berge, et al. J. Pharm. Sci., 66(1), 1977, 1-19.

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