Malate dehydrogenase method

Details Malate dehydrogenase method Malate dehydrogenase method

1982-09-30

1985-09-24

Kepplinger, Esther M.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving oxidoreductase

C12Q 132

Patent

active

045433275

ABSTRACT:
A diagnostic method is disclosed, based on the automated kinetic determination of LD and MD isoenzymes in serum, which utilizes the comparison of two rates of LD and MD activity at different concentrations of substrate. It compares the first activity to the second concentration (activity) to obtain a ratio of activities relative to the two said activities with the first activity in the denominator and the second activity in the numerator and then determining the amount of MD activity enhancement (accelerated activity) by observing the ratio of measured MD activity.

REFERENCES:
patent: 3862010 (1975-01-01), Rush et al.
patent: 4266022 (1981-05-01), Lamprecht
patent: 4311791 (1982-01-01), Bernstein

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