Malate dehydrogenase conjugates for enzyme immunoassays

Details Malate dehydrogenase conjugates for enzyme immunoassays Malate dehydrogenase conjugates for enzyme immunoassays

1977-01-19

1980-03-04

Tanenholtz, Alvin E.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Stablizing an enzyme by forming a mixture, an adduct or a...

435 7, G01N 3114, C07G 702

Patent

active

041916131

ABSTRACT:
Novel conjugated enzyme compositions are provided for use in homogeneous enzyme immunoassays. A wide variety of compounds, particularly drugs, including drugs of abuse, drugs used in repetitive therapeutic applications, hormones, and the like, are conjugated to malate dehydrogenase. The resulting products have a high turnover rate, so as to provide a high multiplication factor when employed in a homogeneous immunoassay, have long storage lives, and allow for the accurate and sensitive detection of compounds of interest.

REFERENCES:
patent: 3850752 (1974-11-01), Schuurs et al.
patent: 3852157 (1974-12-01), Rubenstein et al.

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