Malarial pre-erythrocytic stage polypeptide molecules

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Amino acid sequence disclosed in whole or in part; or...

Reexamination Certificate

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C424S268100, C424S272100, C435S007220, C530S350000, C530S395000, C530S822000

Reexamination Certificate

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07056518

ABSTRACT:
Polypeptide molecules containing at least 10 consecutive amino acids of the amino acid sequence shown inFIG. 2, representing the LSA3 antigen, the following peptides being excluded:RDELFNELLNSVDVNGEVKENILEESQVNDDIFNSLVKSVQQEQQHNVEEVEESVEENDEESVEENVEENVENNDDGSVASSVEESIASSVDESIDSSIE-ENVAPTVEEIVAPTVEEIVAPSVVEKCAPSVEESVAPSVEESVAEMLKER(729S)RDELFNELLNSVDVNGEVKENILEESQVNDDIFNSLVKSVQQEQQHNDELFNELLNSVDVNGEVKENILEESQ, (NRI)LEESQVNDDIFSNSLVKSVQQEQQHNV, (NRII)VESVAPSVEESVAPSVEESVAENVESSV. (729RE)

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David A. Fidock, et al.,Cloning and Characterization of a Novel Plasmodium Falciparum Sporozoite Surface Antigen, Starp, Molecular and Biochemical Parasitology,64, pp. 212-232, 1994.
Debra A. Barnes, et al.,Plasmodium Falciparum: D260. An Intraerythrocytic Parasite Protein, is a Member of the Glutamic Acid Dipeptide-Repeat Family of Proteins, Experimental Parasitology,81, pp. 79-89, 1995.

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