Malaria-specific DNA sequences, expression products thereof, and

Details Malaria-specific DNA sequences, expression products thereof, and Malaria-specific DNA sequences, expression products thereof, and

1993-09-29

1996-12-17

Cunningham, Thomas M.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

435 693, 4352528, 4353201, 530324, 530350, 530395, 536 235, C12N 121, C07H 2104, C07K 14445

Patent

active

055852688

ABSTRACT:
The invention relates to malaria-specific nucleic acid sequences, to the expression products thereof, and to the use thereof. A combination of three of the expression proteins whose nucleic acid sequences were isolated by screening a lambda gt11 gene bank with a monospecific antiserum against the protective 41 kD antigen band from P. falciparum protects Aotus monkeys from a P. falciparum infection in model experiments.

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