Malaria-specific DNA sequences, expression products thereof, and

Details Malaria-specific DNA sequences, expression products thereof, and Malaria-specific DNA sequences, expression products thereof, and

1991-06-27

1993-03-16

Nucker, Christine M.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

25 or more amino acid residues in defined sequence

530350, 530820, 530806, 424 88, 435 697, C07K 1300, C07K 1504, A61K 39015

Patent

active

051945878

ABSTRACT:
The invention relates to malaria-specific DNA sequences, to the expression products thereof, and to the use thereof.
A combination of three of the expression proteins whose DNA sequences were isolated by screening a lambda gt11 gene bank with a monospecific antiserum against the protective 41kD antigen bend from P. falciparum protects Aotus monkeys completely from a P. falciparum infection in model experiments.

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