Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Reduced antigenicity – reduced ability to bind complement – or...
Patent
1981-03-09
1982-08-03
Phillips, Delbert
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Reduced antigenicity, reduced ability to bind complement, or...
2601125R, A61K 3700, C07C10352
Patent
active
043427510
ABSTRACT:
Majusculamide C, a novel cyclic peptide compound which inhibits fungal plant pathogens, process for its preparation from a deep-water blue-green alga, Lyngbya majuscula, and process for inhibiting fungal plant pathogens with and fungicidal compositions containing majusculamide C.
REFERENCES:
D. C. Carter, Marine Natural Products: The Structure of an Unusual Cyclic Depsipeptide from Lyngbya majuscula, a thesis presented to the graduate division of the University of Hawaii, Dec., 1980.
J. S. Mynderse et al., Antileukemia Activity in the Oscillatoriaceae: Isolation of Debromoaplysiatoxin from Lyngbya, Science 196, 538-540, (Apr. 29, 1977).
R. E. Moore, Toxins from Blue-Green Algae, BioScience 27 (12), 797-802, (1977).
R. E. Moore, High Frequency NMR Studies of Some Marine Natural Products, Abstracts, 6th International Symposium on Magnetic Resonance, Banff, Canada, p. 124.
F. Marner et al., Majusculamides A and B, Two Epimeric Lipodipeptides From Lyngbya majuscula Gomont, J. Org. Chem. 42, 2815-2819 (1977).
J. S. Mynderse et al., Malyngamides D and E, Two trans-7-Methoxy-9-methylhexade-4-enamides from a Deep Water Variety of the Marine Cyanophyte Lyngbya majuscula, J. Org. Chem. 43, 4359 (1978).
R. E. Moore, Grant Proposal entitled "Natural Products From Marine Organisms", and Correspondence With National Science Foundation for Grant No. CHE79-25416.
R. L. Pecsok, Grant Proposal entitled "Purchase of 300 MHz Fourier Transform Superconductive Magnet Nuclear Magnetic Resonance Spectrometer", submitted to the National Science Foundation, title pages and pp. 44-45.
J. C. Braekman et al., III International IUPAC Symposium on Marine Natural Products: a Survey, Trends in Pharmacol. Sciences 2, VII-VIX (Feb. 1981).
K. L. Rinehart, Jr., et al., Didemnins: Antiviral and Antitumor Depsipeptides From a Caribbean Tunicate, Science 212, 933-935 (May 22, 1981).
Moore Richard E.
Mynderse Jon S.
Eli Lilly and Company
Harrison Nancy J.
Phillips Delbert
Whale Arthur R.
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