Maize chlorotic dwarf virus genome and uses therefor

Multicellular living organisms and unmodified parts thereof and – Method of introducing a polynucleotide molecule into or... – The polynucleotide alters fat – fatty oil – ester-type wax – or...

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536 2372, 435 691, 4351723, 435419, A01H 500, C12N 1582

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active

058667806

ABSTRACT:
The present invention provides the nucleotide structure and organization of a novel maize chlorotic dwarf virus genome designated MCDV-Tn. Methods for using the complete or partial MCDV-Tn genomic sequence as a probe for diagnostic and other purposes are taught. Methods for inhibiting MCDV-Tn infection are also taught. These methods include the generation of transformed plants capable of expressing MCDV-Tn proteins, either in modified or unmodified form, and antisense sequences targeting MCDV-Tn genomic RNA. Recombinant production of MCDV-Tn proteins in appropriate host cells is also taught.

REFERENCES:
Lopes, J.R.S. et al. (1994) "Leafhopper Transmission and host Plant Range of Maize Chlorotic Dwarf Waikavirus Strains" Phytopathology 84:876-882.
Gingery, R.E., L.R. Nault (1990) "Severe Maize Chlorotic Dwarf Disease Caused by Double Infection" Phytopathology 80:687-691.
Wilson, TMA (Apr. 1993) Proc. Natl Acad. Sci USA 90:3134-3141.
Nejidat et al (1990) Physiologia Plantanum 80: 662-668.

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