Magnetically responsive composition for carrying biologically ac

Details Magnetically responsive composition for carrying biologically ac Magnetically responsive composition for carrying biologically ac

1995-06-07

1997-07-29

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424488, 424489, 424 932, A61K 916, A61K 950

Patent

active

056519893

ABSTRACT:
A magnetically controllable, or guided, carrier composition and methods of use and production are disclosed, the composition for carrying biologically active substances to a treatment zone in a body under control of a magnetic field. The composition comprises composite, volume-compounded ferrocarbon particles of 0.2 to 5.0 .mu.m in size, and preferably between 1.0 and 4.0 .mu.m, containing 1.0 to 95.0% by volume of carbon, and preferably between about 20 and 50%. The particles are produced by a joint deformation of a mechanical mixture of iron and carbon powders. The obtained particles are placed in a solution of a biologically active substance to absorb the substance onto the particles. The combination is administered in suspension.

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Imshennik, et al., "The formation of magnetic iron clusters on activated carbon", Chemical Abstracts Service, Columbis, Ohio; Hyperfine Interact, 57(1-4), 1875-81, 1990; Coden: Hyindn;ISSN: 0304-3843, 1990.
Patent Abstracts of Japan, vol. 008 No. 241 (C-250), 6 Nov. 1984; and JP A-59 122429, Jul. 14, 1984.

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