Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Arterial prosthesis – Drug delivery
Reexamination Certificate
2005-10-14
2010-12-07
Prebilic, Paul (Department: 3774)
Prosthesis (i.e., artificial body members), parts thereof, or ai
Arterial prosthesis
Drug delivery
C424S646000, C600S012000, C604S507000
Reexamination Certificate
active
07846201
ABSTRACT:
A particle including a matrix-forming agent and a polyelectrolyte-amphiphilic agent adduct wherein the polyelectrolyte-amphiphilic agent adduct is in physical communication with the matrix-forming agent. The particle further includes a coated magnetic field-responsive agent and a biomaterial. Methods of making the particle are provided. Also provided are methods of delivery of the biomaterial to a target cell or a target tissue including administering the particle having the matrix-forming agent, polyelectrolyte-amphiphilic agent adduct, the coated magnetic field-responsive agent and the biomaterial; providing a magnetic device associated with the target cell or the target tissue; applying a magnetic force to the particle; and guiding the particle toward the magnetic device by the magnetic force.
REFERENCES:
patent: 3474777 (1969-10-01), Figge et al.
patent: 4176058 (1979-11-01), Grobler
patent: 4345588 (1982-08-01), Widder et al.
patent: 4465518 (1984-08-01), Miyoshi et al.
patent: 4501726 (1985-02-01), Schroder et al.
patent: 5665333 (1997-09-01), Homola et al.
patent: 5843509 (1998-12-01), Calvo Salve et al.
patent: 5889110 (1999-03-01), Hutchinson
patent: 5916539 (1999-06-01), Pilgrimm
patent: 5921244 (1999-07-01), Chen et al.
patent: 2002/0133225 (2002-09-01), Gordon
patent: 2003/0175492 (2003-09-01), Dames et al.
patent: 2006/0041182 (2006-02-01), Forbes et al.
patent: WO 00/43044 (2000-07-01), None
Christian Plank, Ulrike Schillinger, Franz Acherer, Christian Bergemann, Jean-Serge Remy, Florian Krotz, Martina Anton, Jim Lausier and Joseph Rosenecker, The Magnetofection Method: Using Magnetic Force to Enhance Gene Delivery, May 2003, Biol. Chem., vol. 384, pp. 737-747, Walter de Gruyter, Berlin, New York.
Florian Krotz, Cor De Wit, Hae-Young Sohn, Stefan Zahler, Torsten Gloe, Ulrich Pohl and Christian Plank, Magnetofection—A Highly Efficient Tool for Antisense Oligonucleotide Delivery in Vitro and In Vivo, May 2003, Molecular Therapy, vol. 7, pp. 700-710, No. 5, The American Society of Gene Therapy.
M. Laird Forrest, James T. Koerber, and Daniel W. Pack, A Degradable Polyethylenimine Derivative with Low Toxicity for Highly Efficient Gene Delivery, Bioconjugate Chem., 2003, pp. 934-940, vol. 14, American Chemical Society.
Michael A. Gosselin, Wenjin Guo, and Robert J. Lee, Efficient Gene Transfer Using. Reversibly Cross-Linked Low Molecular Weight Polyethylenimine, Bioconjugate Chem., 2001, pp. 989-994, vol. 12, American Chemical Society.
J. L. Arias, V. Gallardo, S. A. Gomez-Lopera, R. C. Plaza, and A. V. Delgado, Synthesis and Characterization of Poly(ethyl-2-cyanoacrylate) Nanoparticles with a Magnetic Core, Oct. 10, 2001, pp. 309-321, vol. 77, Journal of Controlled Release, Elsevier Science B.V.
S. A. Gomez-Lopera, R. C. Plaza, and A. V. Delgado, Synthesis and Characterization of Spherical Magnetite/Biodegradable Polymer Composite Particles, 2001, pp. 40-47, vol. 240, Journal of Colloid and Interface Science, Academic Press.
M. Igartua, P. Saulnier, B. Heurtault, B. Pech, J. E. Proust, J. L. Pedraz, and J. P. Benoit, Development and Characterization of Solid Lipid Nanoparticles Loaded with Magnetite, 2002, pp. 149-157, vol. 233, International Journal of Pharmaceutics, Elsevier Science B.V.
R. H. Muller, S. Maaben, H. Weyhers, F. Specht, and J. S. Lucks, Cytotoxicity of Magnetite-Loaded Polylactide, polylactide/Glycolide Particles and Solid Lipid Nanoparticles, 1996, pp. 85-94, vol. 138, International Journal of Pharmaceutics, Elsevier Science B.V.
Ernst Wagner, Kurt Zatloukal, Matt Cotton, Helen Kirlappos, Karl Machtler, David T. Curiel, and Max L. Birnstiel, Jul. 1992, pp. 6099-6103, vol. 89, Proc. Natl. Acad. Sci., USA.
Christian Plank, Franz Scherer, Ulrike Schillinger, Christian Bergemann, and Martina Anton, Magnetofection: Enhancing and Targeting Gene Delivery with Superparamagnetic Nanoparticles and Magnetic Fields, 2003, pp. 29-32, vol. 13, No. 1, Journal of Liposome Research, Marcel Dekker, Inc.
F. Scherer, M. Anton, U. Schillinger, J. Henke, C. Bergemann, A. Kruger, B. Gansbacher, and C. Plank, Magnetofection: enhancing and targeting gene delivery by magnetic force in vitro and in vivo, 2002, pp. 102-109, vol. 9, Gene Therapy, Nature Publishing Group.
Florian Krotz, Hae-Young Sohn, Torsten Gloe, Christian Plank, and Ulrich Pohl, Magnetofection Potentiates Gene Delivery to Culture Endothelial Cells, 2003, pp. 425-434, vol. 40, S. Karger AG, Basel.
M. De Cuyper, and M. Joniau, Magnetoliposomes Formation and Structural Characterizations, 1988, pp. 311-319, European Biophysics Journal, Springer-Verlag.
Sanaa E. Khalafalla, Magnetic Fluid, Chemtech, Sep. 1975, pp. 540-546.
Majeti N. V. Ravi Kumar, Nano and Microparticles as Controlled Drug Delivery Devices, 2000, pp. 234-258, vol. 3, No. 2, J Pharm Pharmaceut Sci.
David Quintanar-Guerrero, Eric Allemann, Hatem Fessi, and Eric Doelker, 1998, pp. 1113-1128, vol. 24, No. 12, Drug Development of Industrial Pharmacy, Marcel Dekker, Inc.
Isabelle Messai, Severine Munier, Yasemin Ataman-Onal, Bernard Verrier, and Thierry Delair, Elaboration of Poly(ethyleneimine) Coated Poly(D,L-lactic acid) Particles. Effect of Ionic Strength on the Surface Properties and DNA Binding Capabilities, 2003, pp. 293-305, vol. 32, Colloids and Surfaces B: Biointerfaces, Elsevier B.V.
Taeghwan Hyeon, Chemical Synthesis of Magnetic Nanoparticles, 2003, pp. 927-934, Chem Comm, The Royal Society of Chemistry.
MM OW Sullivan, JJ Green, and TM Przybycien, Development of a Novel Gene Delivery Scaffold Utilizing Colloidal Gold-Polyethylenimine Conjugates for DNA Condensation, 2003, pp. 1882-1890, vol. 10, Gene Therapy, Nature Publishing Group.
Ritsuko Ito, Yoshiharu Machida, Takanori Sannan, and Tsuneji Nagai, Magnetic Granules: a novel system for specific drug delivery to esophageal mucosa in oral administration, 1990, pp. 109-117, vol. 61, International Journal of Pharmaceutics, Elsevier Science Publishers B.V. (Biomedical Division).
Christian Plank, Martina Anton, Carsten Rudolph, Joseph Rosnecker & Florian Krotz, Enhancing and targeting nucleic acid delivery by magnetic force, 2003, pp. 745-758, vol. 3, No. 5, Expert Opinion Biol. Ther., Ashley Publications Ltd.
Zachary G. Forbes, Benjamin B. Yellen, Kenneth A. Barbee, and Gary Friedman, An Approach to Targeted Drug Delivery Based on Uniform Magnetic Fields, Sep. 2003, pp. 3372-3377, vol. 39, No. 5, IEEE Transactions on Magnetics.
Janet Fricker, Drug-eluting stents: flashy future or flash-in-the-pan?, Nov. 2001, pp. 1135-1137, vol. 6, No. 22, Drug Discovery Today, Elsevier Science Ltd.
Samer M. Garas, Philip Huber, and Neal A. Scott, Overview of therapies for prevention of restenosis after coronary interventions, 2001, pp. 165-178, vol. 92, Pharmacology & Therapeutics, Elsevier Science Inc.
A. H. Gershlick, Treating atherosclerosis: local drug delivery from laboratory studies to clinical trials, 2002, pp. 259-271, vol. 160, Atherosclerosis, Elsevier Science Ireland, Ltd.
Scott Goodwin, Caryn Peterson, Carl Hoh, and Craig Bittner, Targeting and retention of magnetic targeted carriers (MTCs) enhancing intra-arterial chemotherapy, 1999, pp. 132-139, vol. 194, Journal of magnetism and Magnetic Materials, Elsevier Science B.V.
Christoph Hehrlein, Amina Arab, and Christoph Bode, Drug-eluting stent: the “magic bullet” for prevention of restenosis?, 2002, pp. 417-423, vol. 97, No. 6, Basic Research in Cardiology, Steinkopff Verlag.
Hugh Herr, PhD, Presentation highlights: Prosthetic and orthotic limbs, May/Jun. 2002, pp. 11-12, vol. 39, No. 3, Journal of Rehabilitation Research and Development, VA/NIH Prosthetics Roundtable, http://www.vard.org/jour/02/39/3/sup/herr.htm.
Jing Liu, George Anthony Flores, and Rongsheng Sheng, In-vitro investigation of blood embolization in cancer treatment using magnetorheological fluids, 2001, pp. 209-217, vol. 225, Journal of Magnetism and Magnetic Materials, Elsevier Science B.V.
E. Regar, G. Sianos, and P. W. Serruys, Stent development and local drug delivery, 2001, pp. 227-248, vol. 59, British Medical Bulletin, The British Council.
Rob
Alferiev Ivan
Chorny Michael
Fishbein Ilia
Levy Robert J.
Polyak Boris
Prebilic Paul
RatnerPrestia
The Children's Hospital of Philadelphia
LandOfFree
Magnetically-driven biodegradable gene delivery... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Magnetically-driven biodegradable gene delivery..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Magnetically-driven biodegradable gene delivery... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4219316