Magnetically assisted binding assays using magnetically labeled

Details Magnetically assisted binding assays using magnetically labeled Magnetically assisted binding assays using magnetically labeled

1994-12-01

1995-08-29

Scheiner, Toni R.

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

Carrier is inorganic

435291, 436528, 436534, 436806, 422236, 209214, G01N 33546, G01N 33553

Patent

active

054459710

ABSTRACT:
The present invention provides devices for performing binding assays. Such devices comprise (i) a reaction vessel where unbound and immobilized magnetically-labeled reagent are produced in relation to the amount of said analyte in said test sample; (ii) a separation means for partitioning said immobilized magnetically-labeled reagent and said bound magnetically-labeled reagent; (iii) a magnetic field generator means for the application of a magnetic field to said magnetically-labeled reagent; and (iv) a measurement means to assess the effect of said magnetic field on said magnetically-labeled reagent as a measure of the presence or amount of said analyte in said test sample. The device provided by the instant invention can run, for example, direct indirect, competitive, inhibition and sandwich assay formats.

REFERENCES:
patent: 5252493 (1993-10-01), Fujiwara et al.

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