Magnetically assisted binding assays using magnetically labeled

Details Magnetically assisted binding assays using magnetically labeled Magnetically assisted binding assays using magnetically labeled

1994-12-01

1995-08-29

Scheiner, Toni R.

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

Carrier is inorganic

436528, 436534, 436806, 422236, 209214, G01N 33546, G01N 33553

Patent

active

054459702

ABSTRACT:
The present invention provides assay methods for performing binding assays, wherein the detectable label is a magnetically responsive material. Direct and indirect, competitive and sandwich assay formats are used to partition the magnetically attractable label between a solid phase and a fluid phase in proportion to the presence or amount of analyte in the test sample. The magnetic responsiveness of the magnetically attractable label in one or both phases results in the exertion of a force upon the label. By determining the extent of the force or influence of the force exerted upon the label, the amount of the analyte in the test sample is determined.

REFERENCES:
patent: 5236824 (1993-08-01), Fujiwara et al.
patent: 5252493 (1993-10-01), Fujiwara et al.

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