Magnetic support matrix for enzyme immobilization

Details Magnetic support matrix for enzyme immobilization Magnetic support matrix for enzyme immobilization

1980-10-22

1982-08-10

Naff, David M.

Chemistry: molecular biology and microbiology

Carrier-bound or immobilized enzyme or microbial cell;...

Enzyme or microbial cell is immobilized on or in an...

252430, 435177, 435180, C12N 1114

Patent

active

043439012

ABSTRACT:
A magnetic support matrix for enzyme immobilization is prepared which comprises a porous, refractory inorganic oxide containing ferromagnetic particles dispersed throughout its interior and a polyamine cross-linked with an excess of a bifunctional reagent impregnated therein so as to furnish pendant functional groups. Such a magnetic support matrix does not otherwise substantially decrease loading of subsequently immobilized enzyme, nor in any other way substantially alter the properties of the immobilized enzyme system when compared to that prepared on a non-magnetic support.

REFERENCES:
patent: 2620314 (1952-12-01), Hoekstra
patent: 4102746 (1978-07-01), Goldberg
patent: 4141857 (1979-02-01), Levy et al.
patent: 4152210 (1979-05-01), Robinson et al.
patent: 4177253 (1979-12-01), Davies et al.
patent: 4199614 (1980-04-01), Ziolo
patent: 4289655 (1981-09-01), Bailey
Halling et al., Magnetic Supports for Immobilized Enzymes and Bioaffinity Adsorbents, Enzyme Microb. Technol., vol. 2, 1980, (pp. 2-11).

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