Magnetic sifter

Details Magnetic sifter Magnetic sifter

2006-11-09

2009-11-10

Shibuya, Mark L (Department: 1641)

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

Carrier is inorganic

C436S518000, C436S538000, C209S038000, C209S214000, C209S215000

Reexamination Certificate

active

07615382

ABSTRACT:
The present invention provides a magnetic sifter that is small in scale, enables three-dimensional flow in a direction normal to the substrate, allows relatively higher capture rates and higher flow rates, and provides a relatively easy method of releasing captured biomolecules. The magnetic sifter includes at least one substrate. Each substrate contains a plurality of slits, each of which extends through the substrate. The sifter also includes a plurality of magnets attached to the bottom surface of the substrate. These magnets are located proximal to the openings of the slits. An electromagnetic source controls the magnitude and direction of magnetic field gradient generated by the magnets. Either one device may be used, or multiple devices may be used in series. In addition, the magnetic sifter may be used in connection with a detection chamber.

REFERENCES:
patent: 5655665 (1997-08-01), Allen et al.
patent: 6890426 (2005-05-01), Terstappen et al.
patent: 2004/0009614 (2004-01-01), Ahn et al.
patent: 2005/0100930 (2005-05-01), Wang et al.
patent: 2006/0008823 (2006-01-01), Kemp et al.

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