Surgery – Instruments – Cyrogenic application
Patent
1993-03-23
1995-07-18
Aschenbrenner, Peter A.
Surgery
Instruments
Cyrogenic application
1286535, A61B 1736
Patent
active
054337178
ABSTRACT:
Methods and apparatus for magnetic resonance imaging (MRI) assisted cryosurgery. Optimal probe placements and cooling parameters are calculated prior to cryosurgery using MRI data. A MRI compatible cryoprobe and a stereotactic probe positioning device are provided. The resolution of MR images is enhanced by mounting a radio frequency MR coil on the intracorporeal end of a cryoprobe. During cryosurgery the temperature distribution in the frozen region is solved by determining the boundary of the frozen region and solving the heat equation for the known boundary conditions. During cryosurgery the temperature distribution in the unfrozen region is determined by T1 measurements. The process of freezing is controled using information from the solution of the energy equation in the frozen region and temperature measurements in the unfrozen region. After cryosurgery the extent of the tissue damage may be ascertained using phosphorus-31 and/or sodium-23 spectroscopy with a special coil set on the cryosurgical probe.
REFERENCES:
patent: 3228400 (1966-01-01), Armao
patent: 3618610 (1971-11-01), Hannant
patent: 3662755 (1972-05-01), Rautenbach et al.
patent: 3674031 (1972-07-01), Weiche
patent: 3800552 (1974-04-01), Sollami et al.
patent: 3807403 (1974-04-01), Stumpf et al.
patent: 3886945 (1975-06-01), Stumpf et al.
patent: 3901241 (1975-08-01), Allen, Jr.
patent: 3942519 (1976-03-01), Shock
patent: 3971383 (1976-07-01), van Gerven et al.
patent: 4206609 (1980-06-01), Durenec
patent: 4207897 (1980-06-01), Lloyd et al.
patent: 4341220 (1982-07-01), Perry
patent: 4345598 (1982-08-01), Zobac et al.
patent: 4528979 (1985-07-01), Marchenko et al.
patent: 4554925 (1985-11-01), Young
patent: 4583538 (1986-04-01), Onik et al.
patent: 4618978 (1986-10-01), Cosman
patent: 4724389 (1988-02-01), Hyde et al.
patent: 4740751 (1988-04-01), Misic et al.
patent: 4770171 (1988-09-01), Sweren et al.
patent: 4785246 (1988-11-01), Sugimoto
patent: 4831330 (1989-05-01), Takahashi
patent: 4869247 (1989-09-01), Howard, III et al.
patent: 4882541 (1989-11-01), Haragashira
patent: 4890062 (1989-12-01), Haragashira
patent: 4923459 (1990-05-01), Nambu
patent: 5046498 (1991-09-01), Fishman
patent: 5050607 (1991-09-01), Bradley et al.
patent: 5050608 (1991-09-01), Watanabe et al.
patent: 5078713 (1992-01-01), Varney et al.
patent: 5290266 (1994-03-01), Rohling et al.
Rubinsky et al "Monitoring Cryosurgery . . . ", Cryobiology, vol. 30, pp. 191-199, Apr. 1993.
Vining, E. et al., "Magnetic Resonance Imaging of the Thalamus following Cryothalamotomy for Parkinson's Disease and Dystonia", Journal of Neuroimaging, vol. 1, No. 3, p. 146, Aug. 1991.
Matsumoto, R., et al., "Monitoring of Laser and Freezing-induced Ablation in the Liver with T1-weighted MR Imaging", Journal of Magnetic Resonance Imaging, vol. 2, p. 555, 1992.
Rubinsky, B., et al., "Monitoring Cryosurgery in the Brain and in the Prostate with Proton NMR", Cryobiology, vol. 30, p. 191, Apr. 1993.
Hurst, G. G. et al., "Intravascular (Catheter) NMR Receiver Probe: Preliminary Design Analysis and Application to Canine Iliofemoral Imaging", Magnetic Resonance in Medicine, vol. 24, p. 343, (1992).
Zemtsov, A., et al., "Magnetic Resonance Imaging of Cutaneous Neoplasms: Clinicopathological Correlation", Journal of Dermatological Surgery and Oncology, vol. 17, p. 416, 1991.
Zemtsov, A., et al., "Magnetic Resonance Imaging of Cutaneous Melanocytic Lesions", Journal of Dermatological Surgery and Oncology, vol. 15, pp. 854, 989.
Isoda, H., "Sequential MRI and CT Monitoring in Cryosurgery--An Experimental Study in Rats", Nippon Acta Radiologica, vol. 49, No. 12, p. 17, Dec. 25, 1989.
Isoda, H., "Sequential MRI and CT Monitoring in Cryosurgery--An Experimental Study in Polyvinyl Alcohol Gel Phantom", Nippon Acta Radiologica, vol. 49, No. 12, p. 6, Dec. 25 1989.
Rubinsky, B. et al., "A mathematical model for the freezing process in biological tissue", Proc. R. Soc. Lond. B vol. 234, p. 343, 1988.
Rubinsky, B. et al., "Cryosurgery: advances in the application of low temperatures to medicine", Rev. Int. Froid, vol. 14, p. 1, 1991.
Rubinsky, B. et al., Heat Transfer During Freezing of Biological Materials, In: Tien ed. 1989, Hemisphere Publishing Corp. New York.
Keanini, R., et al., "Simulation and Optimization of Three-Dimensional Multi-Probe Prostatic Cryosurgery", J. Heat Transfer-ASME Trans., vol. 114, p. 796, 1992.
Onik, G., et al., "Ultrasound Guided Hepatic Cryosurgery in the Treatment of Metastic Colon Carcinoma; Preliminary Results", Cancer, vol. 67, p. 901, 1991.
Onik, G., et al., "Percutaneous Transperineal Prostate Cryosurgery Using Transrectal Ultrasound Guidance: Animal Model" Urology vol. 37, p. 277, 1991.
Dickinson, R. J., et al., "Measurement of Changes in Tissue Temperature using MR Imaging," Journal of Computer Assisted Tomography, vol. 10, p. 468, 1986.
Le Bihan, D., et al., "Temperature Mapping with MR imaging of Molecular Diffusion: Application to Hyperthermia," Radiology, vol. 171, p. 853, 1989.
Gilbert, J. C., et al., "Solid-Liquid Interface Monitoring with Ultrasound During Cryosurgery," ASME Paper #85-WA/HT-83, 1985.
Bottomley et al., "A review of .sup.1 H NMR relaxation in pathology; are T.sub.1 and T.sub.2 diagnostic?" Mechanical Physics, vol. 14, p. 1, 1987.
Mulkern et al., "Contrast Manipulation and Artifact Assessment of 3D and 4D RARE sequence," Magnetic Resonance in Medicine vol. 8, p. 557, 1990.
Gilbert John
Pease Grant
Roos Mark
Rubinsky Boris
Wong Sam
Aschenbrenner Peter A.
Egan, III William J.
Peffley Michael
The Regents of the University of California
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