Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent
Patent
1995-06-07
1998-01-13
Kight, John
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Magnetic imaging agent
424 93, 424 9323, A61K 4900, G01N 3100, G01N 3348
Patent
active
057076057
ABSTRACT:
The invention relates to magnetic resonance imaging agents comprising a paramagnetic metal ion bound to a complex wherein said complex comprises a chelator and a blocking moiety convalently attached to said chelator which binds in at least a first coordination site of said metal ion and which is capable of interacting with a target substance such that the exchange of water in at least said first coordination site is increased.
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Fraser Scott
Jacobs Russell
Meade Thomas
Jones Dameron L.
Kight John
Research Corporation Technologies
Silva Robin M.
Trecartin Richard F.
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