Magnetic resonance diagnostic apparatus

Electricity: measuring and testing – Particle precession resonance – Using a nuclear resonance spectrometer system

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

324309, G01V 300

Patent

active

060053909

ABSTRACT:
In an improved INEPT pulse sequence, an excitation pulse, a refocus pulse and an excitation pulse are sequentially applied for .sup.1 H spins. A refocus pulse and an excitation pulse are sequentially applied for .sup.13 C spins that are spin-spin coupled with the .sup.1 H spins. A magnetic resonance signal is acquired from .sup.1 H spins or .sup.13 C spins. The second refocus pulse for .sup.1 H is applied as a slice selective pulse at a time different from the time the first refocus pulse for .sup.13 C is applied. This allows localization to be achieved without adversely affecting the flip angle of the first refocus pulse for .sup.13 C.

REFERENCES:
patent: 4987369 (1991-01-01), Van Stapele et al.
patent: 5166616 (1992-11-01), Doddrell et al.
patent: 5345174 (1994-09-01), Kimmich et al.
patent: 5475308 (1995-12-01), Piotto et al.
patent: 5677628 (1997-10-01), Watanabe et al.
patent: 5894221 (1999-04-01), Watanabe et al.
Won Reinhard Benn et al, "Moderne Pulsfolgen . . . NMR-Spektroskopie" Angew. Chemie, 95, pp. 381-411 (1983).
K. E. Kover et al, "Easy Implementation . . . Filters", Journal of Magnetic Resonance, Series B 101, 1-7 (1993).
Luciano Muller, "Sensitivity Enhanced Detection of Weak Nuclei Using Heteronuclear Multiple Quantum Coherence", Journal of American Chemical Society, vol. 101, (pp. 4481-4484), 1979.
Ad Bax, et al., Journal of American Chemical Society, vol. 105, (pp. 7188-7190), 1983.
Ralph E. Hurd, et al., "Gradient-Enhanced Proton-Detected Heteronuclear Multiple-Quantum Coherence Spectroscopy", Journal of Magnetic Resonance, vol. 91, (pp. 648-653), 1991.
Peter C.M. van Zijl, et al., "In Vivo Proton Spectroscopy and Spectroscopic Imaging of (1-.sup.13 C)-Glucose and Its Metabolic Products", Magnetic Resonance in Medicine, vol. 30, (pp. 544-551), 1993.
Gareth A. Morris, et al., "Enhancement of Nuclear Magnetic Resonance Signals by Polarization Transfer", Journal of the American Chemical Society, vol. 101, (pp. 760-762), 1979.
D.M. Doddrell, et al., "Distortionless Enhancement of NMR Signals by Polarization Transfer", Journal of Magnetic Resonance, vol. 48, (pp. 323-327), 1982.
W.P. Aue, et al., "Localized .sup.13 C NMR Spectra with Enhanced Sensitivity Obtained by Volume-Selective Excitation", Journal of Magnetic Resonance, vol. 61, (pp. 392-395), 1985.
D.G. Morris, et al., "Inept-Enhanced .sup.13 C Spectroscopy Using Double-Tuned Surface Coils", Journal of Magnetic Resonance, vol. 78, (pp. 362-366), 1988.
M. Saner, et al., "Volume-Selective Carbon-13 Spectroscopy by Localized Polarization Transfer", Book of Abstracts of the Society for Magnetic Resonance in Medicine, (p. 1068), 1990.
Hong N. Yeung, et al., "Imaging and Localized Spectroscopy of .sup.13 C by Polarization Transfer", Journal of Magnetic Resonance, vol. 83, (pp. 183-189), 1989.
R.J. Ordidge, et al., "Image-Selected in Vivo Spectroscopy (ISIS). A New Technique for Spatially Selective NMR Spectroscopy", Journal of Magnetic Resonance, vol. 66, (pp. 283-294), 1986.
Geoffrey Bodenhausen, et al., "Natural Abundance Nitrogen-15 NMR by Enhanced Heteronuclear Spectroscopy", Chemical Physics Letters, vol. 69, (pp. 185-189), 1980.
Jesus Ruiz-Cabello, et al., "Gradient-Enhanced Heteronuclear Correlation Spectroscopy. Theory and Experimental Aspects", Journal of Magnetic Resonance, vol. 100, (pp. 282-302), 1992.
Daniel Bruhwiler, et al., "Selective Excitation of .sup.1 H Resonances Coupled to .sup.13 C. Hetero COSY and RELAY Experiments with .sup.1 H Detection for a Protein", Jouranal of Magnetic Resonance, vol. 69, (pp. 546-551), 1986.
Arthur G. Palmer III, et al., "Sensitivity Improvement in Proton-Detected Two-Dimensional Heteronuclear Correlation NMR Spectroscopy", Journal of Magnetic Resonance, vol. 93, (pp. 151-170), 1991.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Magnetic resonance diagnostic apparatus does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Magnetic resonance diagnostic apparatus, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Magnetic resonance diagnostic apparatus will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-508535

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.