Magnetic resonance blood pool agents bound to human serum albumi

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent

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Details

424 91, 424 93, A61K 4900, G01N 3100, G01N 3348

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active

056933088

ABSTRACT:
The present invention provides compositions comprising a contrast agent capable of reversibly binding to thiol groups of blood-borne proteins. The compositions of the invention provide increased residence time of the contrast agent in the vasculature, thus providing effective blood pool contrast agents. The invention also provides methods for imaging a patient comprising administering a composition of the invention and obtaining an image.

REFERENCES:
patent: 4559221 (1985-12-01), Arano et al.
patent: 4647447 (1987-03-01), Gries et al.
patent: 4746505 (1988-05-01), Jones et al.
patent: 5095111 (1992-03-01), Lever et al.
patent: 5138040 (1992-08-01), Moore et al.
patent: 5196515 (1993-03-01), Lever et al.
patent: 5310536 (1994-05-01), Srinivasan
patent: 5393512 (1995-02-01), Vanderheyden et al.
patent: 5401489 (1995-03-01), Born et al.
patent: 5443815 (1995-08-01), Dean et al.
Verbeke et al (1993), European J. of Nuclear Medicine, vol. 20, No. 6, pp. 473-482, "Technetium-99m mercapto albumin as a potential substitute for technetium-99 m labeled red blood cells".
Moore et al (1977), Journal of Labelled Compounds and Radiopharmaceuticals,vol. 13, No. 4, pp. 539-550, "Indium Labeled Particles for Lung Imaging: Homogenous and Heterogeneous phase reactions".
Jenkins (1991), Life Science, vol. 48, pp. 1227-1240, "Detection of Site-Specific binding and co-binding, of Ligands to Macromolecules Using 19FNMR".

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