Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1995-01-19
1997-09-30
Kim, Kay K. A.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
5303911, 5303913, 530404, 530405, 530408, 530409, 435181, 436526, 424 934, C07K 1706, G01N 33547, G01N 33553, A61K 3944
Patent
active
056726872
ABSTRACT:
The invention relates to magnetic protein conjugates of the formula I ##STR1## in which M represents a dispersible magnetically reacting material or particle which carries aminogroups, Ig represents a protein which carries one or more mercapto groups, and X represents an organic chemical structure which links the two ligands by chemical means, to a process for the preparation of protein conjugates of the formula I, and to the use of conjugates of this type for removing cells or soluble bioorganic molecules or components from aqueous salt solutions or body fluids, and to the use thereof within the framework of a diagnostic method or as a diagnostic aid.
REFERENCES:
patent: 4659839 (1987-04-01), Nicolotti et al.
patent: 4671958 (1987-06-01), Rodewell et al.
patent: 4698302 (1987-10-01), Whitehead et al.
patent: 4735796 (1988-04-01), Gordon
patent: 5002883 (1991-03-01), Bienianz et al.
Vartdal et al. Transplantation, vol. 43, No. 3 (1978).
Boyum, Scand. J. Immunol., vol. 5, Suppl. 5 (1976).
Kvalheim et al., Cancer Research, vol. 47 (1987) pp. 846-851.
Treleaven et al., "Removal of neuroblastoma cells from bone marrow with monoclonal antibodies conjugated to magnetic microsheres," The Lancet, 70, 73 (1984).
Blair et al (1983) J. Immunol. Methods 59:129-143.
Imagawa et al (1982) J. Appl. Biochem. 4:41-57.
Keller et al (1975) Hel. Chim. Acta 58 (Fasc. 2) No. 62-63:531-541.
Donges Reiner
Enssle Karlheinz
Hermentin Peter
Kurrle Roland
Seiler Friedrich Robert
Behringwerke Aktiengesellschaft
Kim Kay K. A.
LandOfFree
Magnetic protein conjugates, a process for the preparation there does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Magnetic protein conjugates, a process for the preparation there, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Magnetic protein conjugates, a process for the preparation there will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2257382