Magnetic particle based electrochemiluminescent detection appara

Details Magnetic particle based electrochemiluminescent detection appara Magnetic particle based electrochemiluminescent detection appara

1998-04-27

2000-10-17

Warden, Jill

Chemistry: analytical and immunological testing

Optical result

With fluorescence or luminescence

422 52, 250361C, 436526, G01N 2176

Patent

active

061330434

ABSTRACT:
A method and apparatus for measuring electrochemiluminescence from a sample composition are described wherein magnetically responsive electrochemiluminescent active species are captured on the electrode with the aid of a capture magnet having a configuration such that the magnetic flux lines (or the magnetic field gradient) of at least one magnetic field source therein are compressed and/or dispersed. This capture magnet improves the distribution of the magnetically responsive electrochemiluminescent active species on the electrode surface and reduces interference with the photomultiplier tube, thereby enhancing the ECL signal and improving sensitivity. The improved capture and distribution also allows for shorter assay times.

REFERENCES:
patent: 4554088 (1985-11-01), Whitehead et al.
patent: 4628037 (1986-12-01), Chagnon et al.
patent: 4695392 (1987-09-01), Whitehead et al.
patent: 4695393 (1987-09-01), Whitehead et al.
patent: 4698302 (1987-10-01), Whitehead et al.
patent: 5744367 (1998-04-01), Talley et al.
Kenten et al., Clinical Chemistry, vol. 38, No. 6, Jun. 1992 (pp. 873-879).
Blackburn et al., Clinical Chemistry, "Electrochemiluminescence Detection for Immunoasays", vol. 37, No. 8, 1991. No month available.
Massay, Richard, Biomedical Products, "Electrochemiluminescence: A Novel Detection System . . . ", Oct. 1992.
Kenten, J.H. et al., 37, Clin. Chem., p. 1626-1632 (1991) No month available.
Kenten, J.H. et al. 6, Mol. Cell. Probes, p. 495-503 (1992) No month available.
DiCesare, J. et al., 15, Biotechniques, p. 152 (Jul., 1993).

Affiliated with

Also associated with

Rating

Magnetic particle based electrochemiluminescent detection appara does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Magnetic particle based electrochemiluminescent detection appara, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Magnetic particle based electrochemiluminescent detection appara will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-467488