Magnetic material-physiologically active substance conjugate

Details Magnetic material-physiologically active substance conjugate Magnetic material-physiologically active substance conjugate

1987-08-28

1989-03-21

Dixon, Jr., William R.

Compositions

Magnetic

Chromium or chromium compound containing

252 6253, 252 6254, 252 6256, 252 6257, 128653, 128654, 424 11, 424 2, 424 3, 210695, C04B 3500, C04B 3526

Patent

active

048140988

ABSTRACT:
Disclosed is a conjugate comprising a magnetic material and a physiologically active substance bound to each other through a polyethylene glycol derivative, and a conjugate comprising a magnetic material and a polyethylene glycol derivative bound to each other. According to the present invention, a bioreactor enabling application to or recovery of physiologically active substances under liquid state by utilizing the magnetic properties is provided.

REFERENCES:
patent: 3474777 (1969-10-01), Figge et al.
patent: 4101435 (1978-07-01), Hasegawa et al.
patent: 4169804 (1979-10-01), Yapel, Jr.
patent: 4331654 (1982-05-01), Morris
patent: 4335094 (1982-01-01), Mosbach
patent: 4413070 (1983-11-01), Renbaum
patent: 4554088 (1985-11-01), Whitehead et al.
patent: 4642447 (1987-03-01), Gries et al.
patent: 4645741 (1987-02-01), Inada
patent: 4952773 (1984-06-01), Molday
Hawley, Condensed Chemical Dictionary, 10th Ed., Van Nostrand Reinhold, N.Y., 1981, pp. 831-832.
Biochemical and Biophysical Research Communications, vol. 142, No. 2, Jan. 30, 1987, pp. 291-296.
Biochemical and Biophysical Research Communications, vol. 145, No. 2, Jun. 15, 1987, pp. 908-914.
Biotechnology Letters, vol. 8, No. 12, Dec. 1986, pp. 877-880.

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