Magnetic iron-dextran microspheres

Details Magnetic iron-dextran microspheres Magnetic iron-dextran microspheres

1982-04-05

1984-06-05

Nucker, Christine M.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

436526, 436529, 436530, 435264, 210632, 252 6253, 252 6254, 252 6255, 424 9, A61K 4300, G01N 2700, G01N 3354, D06M 1600

Patent

active

044527730

ABSTRACT:
The invention relates to colloidal sized particles composed of magnetic iron oxide (Fe.sub.3 O.sub.4) coated with a polysaccharide, preferably dextran, or a derivative thereof having pendant functional groups. The particles have a magnetic moment, are electron dense, and are stable and non-aggregating under physiological conditions. They can be covalently bonded to antibodies, enzymes and other biological molecules and used to label and separate cells, cellular membranes and other biological particles and molecules by means of a magnetic field.

REFERENCES:
patent: 3720760 (1973-03-01), Bennich et al.
patent: 3995018 (1976-11-01), Stoquist
patent: 4018886 (1977-04-01), Giaever
patent: 4070246 (1978-01-01), Kennedy et al.
patent: 4101435 (1978-07-01), Hasegawa et al.
patent: 4108975 (1978-08-01), Hales
patent: 4115534 (1978-09-01), Ithakission
patent: 4115535 (1978-09-01), Giaever
patent: 4166102 (1979-08-01), Johnson
patent: 4169804 (1979-10-01), Yapel, Jr.
patent: 4177253 (1979-12-01), Davies et al.
patent: 4278651 (1981-07-01), Hales
patent: 4335094 (1982-06-01), Mosbach
Nye, Clin. Chim. ACTA, 69 (1976), 387-396.
Hersh et al., Clin. Chim. ACTA, 63 (1975), 69-72.

Affiliated with

Also associated with

Rating

Magnetic iron-dextran microspheres does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Magnetic iron-dextran microspheres, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Magnetic iron-dextran microspheres will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1496904