Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2005-02-08
2005-02-08
Forman, BJ (Department: 1634)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S283100, C435S287200, C435S287900, C435S288500, C536S023100
Reexamination Certificate
active
06852493
ABSTRACT:
The invention provides a method for increasing the hybridization rate of nucleic acids in a nucleic acid assay by labeling nucleic acid molecules with paramagnetic labels and activating a magnetic field inducing rapid migration of the labeled molecules to a solid support, where the labeled molecule hybridizes with its complementary pair. The paramagnetic label may be present on the target nucleic acid or the probe nucleic acid, depending upon whether the target or probe are the immobile phase.
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Chin Simon
Ramirez-Vick Jaime E.
Forman BJ
Fox James A.
Heller Ehrman White & McAuliffe LLP
Iris Biotechnologies, Inc.
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