Stock material or miscellaneous articles – Coated or structually defined flake – particle – cell – strand,... – Particulate matter
Reexamination Certificate
2011-03-01
2011-03-01
Le, H. (Holly) T (Department: 1788)
Stock material or miscellaneous articles
Coated or structually defined flake, particle, cell, strand,...
Particulate matter
C427S127000, C427S216000, C427S221000
Reexamination Certificate
active
07897257
ABSTRACT:
The present invention relates to magnetic beads suitable for, for example, isolation of proteins, cells, and viruses and also for diagnostic applications and cell cultivation. The magnetic beads are composite beads with an inner core of metal particles, which are coated with an inert synthetic polymer and these are then enclosed in a hydrophilic porous polymer, preferably agarose. This provides porous biocompatible beads without metal leakage. The beads may be used for cell cultivation or for chromatography. When the beads are used for chromatography the agarose layer is preferably provided with ligands having affinity for selected biomolecules.
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Alterman Mathias
Axen Andreas
Glad Gunnar
Lindstrom Dag
Meyer Ulrika
GE Healthcare Bio-Sciences AB
Ji Yonggang
Le H. (Holly) T
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