Magnesium-zirconium complexes useful as antiperspirants

Drug – bio-affecting and body treating compositions – Effervescent or pressurized fluid containing – Organic pressurized fluid

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2604293, 424 66, A61K 734

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active

040215369

ABSTRACT:
Astringent compositions useful as antiperspirants are provided by forming a complex of a magnesium salt and an astringent zirconium compound, particularly zirconium oxy and hydroxy salts, such that the weight ratio of the zirconium content to the magnesium content in the complex expressed as the oxides will be in the range of about 30:1 to 1:1. The preferred amount of magnesium, expressed as the oxide, in an aqueous antiperspirant solution containing an effective amount of the complex will be greater than about 3 weight percent. Preferred compositions include complexes of magnesium-amino acid salts, such as magnesium glycinate, plus zirconyl hydroxy chloride in which the ratio of zirconium to magnesium is about 10:1 to 3:1 and the total content of magnesium plus zirconium is about 5 to 15 weight percent and preferably about 5 to 10 weight percent, both expressed as the oxides. Buffers such as urea, amino acids, salts of amino acids, etc. may also be included in the complexes to maintain a pH of at least about 3 in aqueous solutions of the complex. The various complexes of the invention may be used in conventional antiperspirant forms, including aqueous solutions, aerosol sprays, powder-in-oil aerosol sprays, creams, lotions, cream sticks, etc.

REFERENCES:
patent: 2236387 (1941-03-01), Wallace et al.
patent: 2814584 (1957-11-01), Daley
patent: 2814585 (1957-11-01), Daley
patent: 2854382 (1958-09-01), Grad
patent: 3405153 (1968-10-01), Jones et al.
patent: 3407254 (1968-10-01), Siegal et al.
patent: 3792068 (1974-02-01), Luedders et al.

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