MAGE-A1 peptides presented by HLA class II molecules

Details MAGE-A1 peptides presented by HLA class II molecules MAGE-A1 peptides presented by HLA class II molecules

2007-01-02

2007-01-02

Schwadron, Ronald B. (Department: 1644)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Cancer cell or component thereof

C530S323000, C530S324000, C530S325000, C530S326000, C530S327000, C530S328000, C530S403000, C530S806000, C530S828000, C530S332000, C424S184100, C424S185100, C424S192100, C424S193100, C424S277100, C514S002600, C514S012200, C514S013800, C514S014800, C514S015800, C514S885000

Reexamination Certificate

active

09336091

ABSTRACT:
The invention provides isolated HLA DRB1*15-binding peptides consisting of the amino acid sequence set forth as SEQ ID NO:7 with 0–10 amino acids added to either or both ends of the amino acid sequence set forth as SEQ ID NO:7, and an endosomal targeting signal comprising an endosomal targeting portion of human invariant chain Ii or LAMP-1.

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Topalian, S.L.,Current Opinion in Immunol., 6: 741-745 (1994).

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