Mage-3 peptides presented by HLA class II molecules

Details Mage-3 peptides presented by HLA class II molecules Mage-3 peptides presented by HLA class II molecules

1997-09-12

1999-10-12

Hutzell, Paula K.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 14, 514 15, 530 26, 530 27, 530 28, A61K 3804, A61K 3810, A61K 3800

Patent

active

059655356

ABSTRACT:
The invention describes the HLA class II binding peptides encoded by the MAGE-3 tumor associated gene, as well as nucleic acids encoding such peptides and antibodies relating thereto. The peptides stimulate the activity and proliferation of CD4.sup.+ T lymphocytes. Methods and products also are provided for diagnosing and treating conditions characterized by expression of the MAGE-3 gene.

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