Macroscopic sweat test for cystic fibrosis

Details Macroscopic sweat test for cystic fibrosis Macroscopic sweat test for cystic fibrosis

1998-09-04

1999-11-02

Clardy, S. Mark

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

424 111, 424 92, 206223, 206569, 206570, A61K 4900, G01N 3100, G01N 3348

Patent

active

059764996

ABSTRACT:
The present invention relates to methods of diagnosing CF comprising: stimulating sweat production via .beta.-adrenergic pathway, by increasing cAMP production; collecting sweat into a sweat collection device; determining the sweat rate as a function of the weight of the sweat collected; correlating the sweat rate with the functional state of CFTR and/or presence or absence of CF. The invention also relates to methods of screening compounds for treatment of cystic fibrosis.

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