Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1995-06-02
1997-07-22
Elliott, George C.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 695, 4351723, 4352523, 4353201, 435 9141, 435348, 4353651, 435358, 435419, 435325, 435366, 536 231, 536 235, C07H 2104, C12N 1519, C12P 2102
Patent
active
056502958
ABSTRACT:
The present invention relates to a human MIF-3 and DNA (RNA) encoding such polypeptide. Also provided is a procedure for producing such polypeptide by recombinant techniques and antibodies and antagonists against such polypeptide. Also provided are methods of using the polypeptide therapeutically for treating cancer, infections, acceleration of wound healing, stimulating the immune system, as an anti-inflammatory. Methods of using antibodies and antagonists for therapeutic purposes, is also disclosed, for example, for treating lethal endotoxaemia, ocular inflammation and diagnosing immune diseases. Also disclosed are diagnostic methods for detecting conditions related to a mutation in a nucleic acid sequence encoding a polypeptide of the present invention and altered levels of the polypeptide of the present invention.
REFERENCES:
PCT International Search Report.
DD 230876, Abstract Only.
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Fitzgerald Lisa M.
Li Haodong
Elliott George C.
Human Genone Sciences, Inc.
McGarry Sean
Mullins J. G.
Olstein Elliot M.
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