Macrophage colony stimulating factor-.gamma.

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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4353201, 530399, 536 27, C12P 2102, C07K 1300, C12N 1527

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active

051716755

ABSTRACT:
A macrophage colony stimulating factor, M-CSF.gamma., which is a primary translation product of an alternative mRNA splicing event and is a precursor to biologically active M-CSF. DNA sequences encoding M-CSF.gamma. and recombinant expression vectors comprising the DNA sequences.

REFERENCES:
Mount, Nuc. Acids Res. v. 10, 1982, pp. 459-472.
Das et al., "Human CSF-1 Radioimmunoassay: Resolution of Three Subclasses of Human CSFs," Blood 58:630-641 (1981).
Waheed and Shadduck, "A Rapid Technique for the Purification of Human Urinary CSF," Exp. Hematol. 12:434 (1984).
Stanley and Heard, "Factors Regulating Macrophage Production and Growth . . . . " J. Biol. Chem. 252:4305-4312 (1977).
Wang and Goldwasser, "Purification of a Human Urinary Colony-Stimulating Factor," J. Cell Biochem. 21:263 (1983).
Kawasaki et al., "Molecular Cloning of a Complementary DNA Encoding Human Macrophage-Specific Colony-Stimulating Factor (CSF-1)", Science 230: 291-296 (1985).
Wong et al., "Human CSF-1: Molecular Cloning and Expression of a 4-kb cDNA Encoding the Human Urinary Protein," Science 235:1504-1508 (1987).

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