Macromolecularized adenine derivatives

Details Macromolecularized adenine derivatives Macromolecularized adenine derivatives

1978-02-22

1980-04-22

Coughlan, Jr., Paul M.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

536 26, 536 27, 536 28, 544229, 544276, C07H 1920, C07C10352

Patent

active

041994981

ABSTRACT:
A method is disclosed for preparing functionalized adenine derivatives, said method comprising the step of reacting a compound which contains an adenine nucleus which has been halogen substituted in the 8-position, with a compound having the general formula N.sup.+- S--(CH.sub.2).sub.n --CO0.sup.- M.sup.+ wherein M.sup.+ is the ion of an alkali metal and n is an integer, the reaction being carried out in a polar aprotic solvent. Procedures for preparing macromolecularized adenine compounds are also indicated by reacting a functionalized adenine derivative with a polymer which has at least one primary or secondary aminic group in its structure.

REFERENCES:
patent: 4088639 (1978-05-01), Zappelli et al.

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