Macromolecular structure for boron neutron-capture therapy

Details Macromolecular structure for boron neutron-capture therapy Macromolecular structure for boron neutron-capture therapy

1997-02-27

1999-01-05

Ambrose, Michael G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Phosphorus esters

C07F 909

Patent

active

058565515

ABSTRACT:
A general synthetic method has been developed for the rapid and efficient production of a variety of boron-rich macromolecules suitable for conjugation with of inclusion in receptor-mediated delivery systems as well as other delivery systems. Preparation techniques have been developed to yield precisely ordered oligophosphates which are soluble, hydrophilic, may be homogeneous, and may be prepared with a variety of functional groups.

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