Macromolecular CDP-choline derivatives, process for their prepar

Details Macromolecular CDP-choline derivatives, process for their prepar Macromolecular CDP-choline derivatives, process for their prepar

1986-09-30

1988-09-20

Schofer, Joseph L.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

424 81, 525375, 525383, 525384, 5253296, 5253297, 526263, A61K 3174

Patent

active

047724633

ABSTRACT:
CDP-choline derivatives with macromolecules containing carboxy groups, such as polyacrylates, polymethacrylates, polyglutamates, polyaspartates and polymaleates, or copolymers of acrylic acid and methacrylic acid with methyl acrylate, methyl methacrylate or acrylamide.
The polymeric derivatives of the invention gradually release CDP-choline, due to the action of enzymes present in the organism, thus exerting also a protective effect on the CDP-choline molecule.

REFERENCES:
Chem. Abstracts, vol. 105, entry 61003m.
Chem. Abstracts, vol. 98, entry 73157q.

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