Macrolides

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C540S456000

Reexamination Certificate

active

06852729

ABSTRACT:
A mixture comprising a poly-ene macrolide and an antioxidant. Preferably, the poly-ene macrolide is rapamycin and the antioxidant is 2, 6-di-tert.-butyl-4-methylphenol. The presence of the antioxidant improves the stability of the poly-ene macrolide to oxidation.

REFERENCES:
patent: 4079128 (1978-03-01), Lin et al.
patent: 4080445 (1978-03-01), Lin et al.
patent: 0 041 795 (1981-12-01), None
patent: 0 329 460 (1989-08-01), None
patent: 0 423 714 (1991-04-01), None
patent: WO 9409010 (1994-04-01), None
patent: WO 9703654 (1997-02-01), None
patent: WO 9804279 (1998-02-01), None
patent: WO 9833482 (1998-08-01), None

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