Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1984-07-12
1986-04-08
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
536 71, A61K 3171, C07H 1508
Patent
active
045813469
ABSTRACT:
C-8, 20-cyclo-derivatives of the macrolide antibiotics tylosin, desmycosin, macrocin, lactenocin, 2'"-O-demethylmacrocin and 2"-O-demethyllactenocin, which inhibit pathogenic bacteria, especially gram-positive bacteria, and Mycoplasma species, and pharmaceutical compositions thereof, are provided.
REFERENCES:
patent: 3178341 (1965-04-01), Hamill et al.
patent: 3326759 (1962-07-01), Hamill et al.
patent: 4345069 (1982-08-01), Sakakibara et al.
patent: 4385116 (1983-05-01), Baltz et al.
Matsubara et al., "Chemical Transformation of Tylosin, a 16-Membered Macrolide, and Its Structure-Activity Relationship," Chem. Pharm. Bull. 30(1) 97-100 (1982).
Brown Johnnie R.
Eli Lilly and Company
Harrison Nancy J.
Peselev Elli
Whale Arthur R.
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