Macrolide compounds containing biotin and photo-affinity...

Details Macrolide compounds containing biotin and photo-affinity... Macrolide compounds containing biotin and photo-affinity...

2011-08-02

2011-08-02

Peselev, Elli (Department: 1623)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

Reexamination Certificate

active

07989600

ABSTRACT:
The present invention relates to new macrolide compounds represented by the general structure I,wherein M is a macrolide, P is a photo-affinity group bearing subunit containing biotin, and L is a linking molecule, and to their pharmaceutically acceptable salts and solvates, to processes and intermediates for their preparation and to the use of these compounds for the macrolide target identification.

REFERENCES:
patent: 2005/095014 (2005-04-01), None
Arevalo et al., “Synthesis and Biological Activity of Photoactive Derivatives of Erythromycin,”Journal of Medicinal Chemistry, V32 N9, 1989, pp. 2200-2204.
Arevalo et al.,Journal of Biological Chemistry, V263 N1, 1988, pp. 58-63.
Vince et al.,Antimicrobial Agents and Chemotherapy, V9 N1, 1976, pp. 131-136.
Sherman et al., “Synthesis and biological investigation of new 4″-malonyl tethered derivatives of erythromycin and clarithromycin,”Bioorganic&Medicinal Chemistry Letters, V 16 N6, 2006, pp. 1506-1509.
Fleming, “Chemical Reagents in Photoaffinity Labeling,”Tetrahedron, V51 N46, 1995, pp. 12479-12520.

Affiliated with

Also associated with

Rating

Macrolide compounds containing biotin and photo-affinity... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Macrolide compounds containing biotin and photo-affinity..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Macrolide compounds containing biotin and photo-affinity... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2702280