Macrolide compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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549264, A61K 31365, C07D31500

Patent

active

051128543

ABSTRACT:
Compounds of formula (1) ##STR1## wherein R.sup.1 represents a methyl, ethyl or isopropyl group; Y.sup.1 is --CH.sub.2 --, Y.sup.2 is --CH-- and X represents ##STR2## [where R.sup.2 represents a hydrogen atom or a group OR.sup.6 (where OR.sup.6 is a hydroxy group or a substituted hydroxyl group having up to 25 carbon atoms) and R.sup.3 represents a hydrogen atom, or R.sup.2 and R.sup.3 together with the carbon atom to which they are attached represent >C.dbd.O, >C.dbd.CH.sub.2 or >C.dbd.NOR.sup.7 (where R.sup.7 represents a hydrogen atom, a C.sub.1-8 alkyl group or a C.sub.3-8 alkenyl group and the group >C.dbd.NOR.sup.7 is in the E configuration)] or --Y.sup.1 --X--Y.sup.2 represents --CH.dbd.CH--CH-- or --CH.sub.2 --CH.dbd.C--; R.sup.4 represents a group OR.sup.6 as defined above and R.sup.5 represents a hydrogen atom, or R.sup.4 and R.sup.5 together with the carbon atom to which they are attached represent >C.dbd.O or >C.dbd.NOR.sup.7a ( where R.sup.7a is as defined above for R.sup.7); and one of R.sup.8 and R.sup.9 represents an alkoxyalkoxy group optionally interrupted by an oxygen atom or an alkoxy group and the other represents a hydrogen atom or R.sup.8 and R.sup.9 together with the carbon atom to which they are attached represent >C.dbd.NOR.sup.7b (where R.sup.7b is as defined above for R.sup.7), and salts thereof.
These compounds may be used to control nematode, acarine, insect or other pests.

REFERENCES:
patent: 4806527 (1989-02-01), Christensen et al.

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