Macrocyclic tetraazacyclododecane conjugates and their use as di

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Attached to antibody or antibody fragment or immunoglobulin;...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

424 9363, 424 165, 4241791, 424 169, 540465, 540474, 5303913, 534 10, 534 16, A61K 5100, A61B 5055, C07K 1600, C07F 500

Patent

active

057560650

ABSTRACT:
A group conjugates having a functionalized polyaminocarboxylate chelant that form complexes with rare earth-type metal ions, covalently attached to an antibody or antibody fragment, can be used for therapeutic and/or diagnostic purposes.

REFERENCES:
patent: 4454106 (1984-06-01), Gansow et al.
patent: 4472509 (1984-09-01), Gansow et al.
patent: 4647447 (1987-03-01), Gries et al.
patent: 4678667 (1987-07-01), Meares et al.
patent: 4885363 (1989-12-01), Tweedle et al.
patent: 4994560 (1991-02-01), Kruper et al.
patent: 5053503 (1991-10-01), Dean et al.
patent: 5057302 (1991-10-01), Johnson et al.
patent: 5342936 (1994-08-01), Parker et al.
patent: 5435990 (1995-07-01), Cheng et al.
patent: 5484893 (1996-01-01), Parker et al.
patent: 5512443 (1996-04-01), Schlom et al.
Mears et al., Anal. Biochem. 142, 68-78 (1984).
Krejcarek et al., Biochem. and Biophys. Res. Comm. 77, 581-585 (1977).
Westerberg et al., J. Med. Chem. 32(1), 236-244 (1989).
Franz et al., Nucl. Med. Biol. 14(5), 479-484 (1987).
Moi et al., J. Am. Chem. Soc. 110, 6266-6267 (1988).
Brittain et al., Inorg. Chem. 23, 4459-4466 (1984).
Desreux et al., Nucl. Med. Biol. 15(1), 9-15 (1988).
Sherry et al., Inorg. Chem. 28, 620-622 (1988).
Washburn et al., Nucl. Med. Biol. 15(6), 707-711 (1988).
Morrison and Boyd, Organic Chemistry 3rd Ed. 360-363 (1973).
Tweedle et al., Proceed 34th Annul. Meetg., 28(4), 705 Abstract No. 626 (1987).
Forsberg et al., Inorg. Chem., 10(12), 2656-2600 (1971).
Forsberg et al., Inorg. Chem. 8(4), 883-888 (1969).
Arzneimittel Wirkungen, pp. 46-55 (1981).
J. March, Advanced Organic Chemistry, pp. 145-150 (1984).
Borch et al., J. Am. Chem. Soc. 93(12), 2897-2004 (1971).
Mattson et al., J. Org. Chem. 55, 2552-2554 (1990).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Macrocyclic tetraazacyclododecane conjugates and their use as di does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Macrocyclic tetraazacyclododecane conjugates and their use as di, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Macrocyclic tetraazacyclododecane conjugates and their use as di will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1957154

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.