Macrocyclic lactones as musk fragrance enhancers

Perfume compositions – Perfume compositions – Ring containing active ingredient

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549266, H61K 746, C07D31300

Patent

active

060081856

ABSTRACT:
Compounds of the formulae ##STR1## in which R is hydrogen or methyl, and the dashed lines represent an additional bond in the 11- or 12-position,
have extraordinary olfactory properties.

REFERENCES:
patent: 3856815 (1974-12-01), Hopp et al.
patent: 3890353 (1975-06-01), Becker
patent: 5319104 (1994-06-01), Hopp et al.
Sugimara et al., Nippon Kagaku Kaishi, 3:425 (1985).
AG Cameron et al., J. Chem. Soc., Perkin Trans. I, 161 (1986).
R.L. Funk et al., Tetrahedron 42 (1986), 42:2831 (1986).
S.L. Schreiber et al., J. Am. Chem. Soc. 102, 6165 (1980).
Kostova et al., Helv. Chim. Acta 78:440 (1995).
Kalina Kostova et al., "Synthese von Tetradecano-14-lacton durch Ringerweiterung" Helvetica Chimica Acta, vol. 78, pp. 440-446 (1995).

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